This Week in Pharma and Biotech: Biomarkers, Drug Approvals and More

The Weekly Roundup newsletter curates the top five - deals, pipeline, funding, and news from the past week.

The complete list is available here: Industry Updates

🤝Deals and Collaborations

1️⃣ EQL Pharma out-licenses Methenamine Hippurate, a medicine for recurrent urinary tract infections, to Dr. Pfleger Arzneimittel for the German market. //Read more

2️⃣ Bayer and Cedilla Therapeutics agree to license CyclinE1/CDK2 complex inhibitors. Bayer gets full rights, Cedilla gets upfront and milestone payments. //Read more

3️⃣ Impact Therapeutics sells rights to two PARP inhibitors to Eikon Therapeutics. Eikon will advance IMP1734 into clinical trials and IMP4297 into Phase II/III trials. //Read more

4️⃣ PharmaEssentia partners with Pint-Pharma to bring BESREMi, a treatment for rare blood cancer, to Latin America. //Read more

5️⃣ Terran Biosciences and Pierre Fabre agree to an exclusive global licensing deal for idazoxan, a late-stage schizophrenia treatment. //Read more

⏫ Pipeline and Approvals

1️⃣ Neurology: Marinus Pharma wins EU nod for pediatric CDD seizures drug. CHMP recommends ZTALMY for CDD seizures in children and adults. CDD is rare genetic disorder with early seizures, neuro issues. //Explore further

2️⃣ Hematology: EMA backs Samsung's eculizumab biosimilar Epysqli for PNH. CHMP recommends approval for PNH in adults and children. Epysqli will be Samsung Bioepis' first hematology biosimilar, expanding its portfolio. //Explore further

3️⃣ Genetic disorder: FDA approves Analog, Dipharma's 20mg generic nitisinone capsules, completing range for hereditary tyrosinemia type 1. //Explore further

4️⃣ Genetic disorder: CANbridge gets China nod to launch first pruritus drug Livmarli for Alagille syndrome patients. //Explore further

💰 Funding

1️⃣ Pneumagen raises £8m to accelerate Phase 2 trials of Neumifil for preventing & treating viral respiratory infections. The funding will advance Neumifil's clinical development for COPD patients with virus-induced exacerbations. //Learn more

2️⃣ Lynk Pharma Closes $28 Million C1 Round for Cancer and Autoimmune Drugs. The funding will advance its portfolio of first/best small molecule candidates for oncology and autoimmune diseases. Lynk is developing second and third-gen JAK inhibitors while exploring novel targets. //Learn more

3️⃣ eXmoor pharma raises $35m to boost cell and gene therapy production. The funding will support the launch of its 65,000 sq ft GMP facility to expand cell and gene therapy production capability. //Learn more

4️⃣ Violet Therapeutics raises $10.6 million in seed funding led by the Dementia Discovery Fund. Violet is advancing a first-in-class program targeting neuroinflammation for indications like Alzheimer's. //Learn more

5️⃣ Hememics Biotech raises a $2 million seed round for its biochip reader device. The device has 32 graphene sensors and bio-preservatives to provide results in under 5 minutes. Data can be uploaded to a center via a cell phone. //Learn more

📰 Interesting News

1️⃣ New blood biomarkers may predict which healthy elderly will develop Alzheimer's. Testing over 1,000 healthy elderly found only those with amyloid burden and markers of abnormal astrocyte activation progressed to Alzheimer's. Crucial for Alzheimer's drug development. //Find out more

2️⃣ New approach improves cancer treatment and minimizes side effects. Scientists found a way to improve immune checkpoint blockade cancer treatment by targeting tumor-positive lymph nodes. This generates a strong response against local and systemic metastases while reducing side effects. //Find out more

3️⃣ Can India Create 50k Biotech Startups? 2021 saw a record 1000+ new biotech startup registrations, per the Bioeconomy Report 2022. Currently, India has 95,000 startups listed on Startup India, including over 5,000 biotech startups. //Find out more

4️⃣ Cutting carbs at breakfast may help with Type 2 diabetes. Researchers found switching from a low-fat breakfast like oatmeal to a low-carb, high protein and fat meal like eggs and bacon can help people with Type 2 diabetes better manage blood sugar for most of the day. //Find out more

5️⃣ Eat right, live longer: Could a moderate protein diet be the fount of youth? Researchers fed mice different amounts of protein. Mice on moderate protein diets were metabolically healthier. These findings could help develop nutritional interventions to improve human metabolic health. //Find out more